• Confoscan 4 is a confocal scanning microscope that allows to inspect human corneal layers in vivo, in a non-invasive way, by recording automatically a sequence of digital images taken all throughout the cornea.


• The Confoscan 4 is a fully digital, corneal confocal microscope that allows a user to view and image human corneal layers in vivo.


• The confocal arrangement consists of one slit that illuminates the tissue and a second slit that filters the reflected light from unfocused layers.


• The user can view, magnify, measure, and photograph separate layers of the transparent structures and tissues of the cornea. One examination records 350 different images.

• Total cornea Confocal Scanning Microscope - Use of 40x probe


• No contact Endothelial Scanning Microscope - Use of 20x probe


• Optical Pachymeter - Use of 40x probe with Z-Ring

• The 25 frames per second image acquisition, combined with the auto-alignment software, allow for easy and fast automatic exam acquisition.


• The system can be programmed for full or partial thickness corneal scans.

• Auto-alignment is a sophisticated software that moves the optical head to the apex starting from off-the-center landing positions.

• Multiple internal fixation targets improve image stability and patient comfort during the exam and allow central and peri -central inspections.

• Confoscan 4 can work as a standalone unit (no computer required) thanks to its embedded micro-computer and display.


• Exams can be optionally stored on an external computer featuring the NAVIS software.

• Confoscan 4 is based on the Linux platform for maximum reliability and performance.


• System boots up in 40”


• Operative System is read-only for a stable performance in time


• Hot switch-off allowed

• The new 20x probe works in air at 12 mm from the corneal apex, allowing fully no-contact endothelial exams with absolute patient comfort.


• No anesthetic nor gel required low light level dedicated auto alignment

• The Z-ring is an optional, detachable, contact element, connected to an internal sensor


• Used to continuously monitor the position of the eye with respect to the probe


• Achieving stabilized scans, accurate pachymetry and locating of intra-corneal structures.


• By measuring the distance between the endothelial and epithelial peaks in each scan one gets optical pachymetry.


• In addition, the Z-ring system actively stabilizes the pressure applied to the eye.

• Automatic cell analysis software detects overall density, number of sides and area of each cell as well as overall pleomorphism and polimegathism indices.


• Fully Automatic, Semi-Automatic, Manual Mode and Customisable exam parameters are available with the unit. This allows you to choose the corneal layers to be scanned - Endothelium, Epithelium or Full cornea scan in one unique patient exam.

• The new confocal setup provides improved image contrast, resolution and homogeneity, down to endothelium.


• Furthermore, scanning noise is eliminated due to the new standing slits.

• High speed in-vivo histology achieved with maximum patient comfort due to the 2 mm working distance objective: gel is placed between the cornea and the objective ensuring no deformation is exerted to the cornea during an exam.

• A 2 mm working distance and a drop of gel ensure that there is no contact or pressure applied to the cornea

User defined automatic examination

• Designed for easy operation


• Joystick control of exam sequence


• Automatic recording of the exam or with user defined parameters, such as corneal thickness, number of passes, and Image Interval

Video Frame Features

• 500 X Magnification


• 5± µm Optical Separation


• Each video frame display a 460 x 345 µm thick corneal layer being focused


• 2 mm working distance (through gel)

• 250 X Magnification


• 5± µm Optical Separation


• Each video frame display a 460 x 690 µm thick corneal layer being focused


• 12 mm working distance (through air)

Z - Scan

• Represents the intensity of reflected light of each image


• Optical Pachymetry


• Locates the image of regard


• Locates structures relative to one another


• Playback of selected portion of images

• The curve represents the intensity profile of reflected light at each corneal layer


• The automatic Z-Scan feature provides the physician with a detailed display of corneal thickness


• Comparison between exams using light reference data

• The number of acquired curves and the scanning depth are user definable


• The average curve of multiple passes can be calculated in order to avoid unwanted effects.


• A smoothed and average curves can be displayed

• The Z-Scan curve can also be used for review of the exam sequence.


• Moving the cursor along the wave displays the image of the corresponding corneal layer.